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MigraComfort™

Clinically Tested Petadolex®

Butterbur Extract

gray left   Product Profile  |  50 mg Undefined   gray right


  • Clinically shown to relieve vascular smooth muscle tension by inhibiting leuketrine synthesis.

  • Uses a patented, standardized extract of butterbur called Petadolex®, which contains the biologically active compounds petasin and isopetasin.

  • Petadolex® process also removes the toxic pyrrolizidine alkaloids from the butterbur plant, ensuring that MigraComfort uses one of the safest and most potent butterbur formulas ever developed.


The perennial shrub Petasides hybridus has been at the center of global herbalism for hundreds of years. Commonly known as butterbur, this powerful herb has a multitude of benefits that have been utilized by Romans, ancient Greeks, and Renaissance Europeans alike. More recently, however, the Native Americans re-discovered butterbur as a powerful aid in managing episodic head discomfort. Fusing these traditional practices with modern research, scientists have now developed a potent butterbur extract called Petadolex®, the patented and standardized ingredient used in Planetary Herbals MigraComfort.

It is a fact that specific vascular imbalances in the brain cause tens of millions of Americans to experience episodes of head discomfort each year. Those who experience it will tell you�occasional head discomfort can drastically limit your daily routine and slow down the pace of your life. As the newest formula of a millennium-old herb, Planetary Herbals MigraComfort provides a way to take control of these episodes so that you don't miss a beat.

Modern Enhancement of an Ancient Herb
The power of MigraComfort lies in its specially formulated extract of the traditional herb butterbur. For centuries butterbur has been at the center of herbal healthcare, and now with the help of 21st century research, butterbur is formulated to combat episodic head discomfort as a standardized, clinically-evaluated extract called Petadolex. The key to Petadolex's® patented extract is a hyper-efficient extraction of butterbur's main tonifying components, petasin and isopetasin. Research indicates that these two substances have strong vasodilatory properties, and also support healthy inflammatory response through their inhibition of leukotriene synthesis. With Petadolex®,researchers found a new way to extract both petasin and isopetasin from the rhizome of the shrub where they are found in the highest concentration. This standardized extract also involves a patented process to remove the toxic pyrrolizidine alkaloids ensuring that MigraComfort uses one of the safest and most potent butterbur formulas ever developed.

Clinically Demonstrated Effectiveness for Episodic Head Discomfort
Researchers at the University of Munich in Germany conducted a clinical, placebo-controlled, double blind study on the effectiveness of Petadolex® to relax cranial blood vessels. Subjects involved were given a four-week run-in phase followed by a 12-week phase where they were administered either 100 mg/day of Petadolex® or a placebo. Compared to the baseline, the frequency of episodes decreased during the study by a maximum of 60%. Intensity and duration of the episodic head discomfort were also diminished. The results of the 1996 study, along with many others, demonstrate that the special Petadolex® formula may be effective in relieving some kinds of occasional head discomfort.

Natural Cerebral Balance
Healthy, smooth cerebral blood flow is an integral component in your overall well-being. The vasodilatory compounds found in Planetary Herbals MigraComfort naturally relax constricted arteries and smooth muscle�giving you the support your body needs to maintain a healthy balance.

Planetary Herbals integrates the best of worldwide herbal traditions with modern clinical research to provide reliable, expertly crafted, superior quality herbal supplements. It is both our commitment to healthy alternatives and our trust in the health-promoting properties of the planet which enables Planetary Herbals to offer the finest herbal supplements available.



Expanded Label Copy


50 mg Undefined

gray left   Product Profile  |  50 mg Undefined   gray right

Supplement Facts for 50 mg Undefined
Serving Size: 1 Softgel
  Amount %DV
Petadolex® Purple Butterbur Root Extract - (Petasites hybridus) standardized to 7.5 mg petasins 50 mg  

Other Ingredients: middle chain triglycerides, gelatin, glycerol, sorbitol, purified water, and riboflavin.

Warning: Do not use this product if you are pregnant, may become pregnant, breastfeeding, or have any liver disease. If persistent symptoms occur such as upper right abdominal pain, nausea, vomiting, or jaundice, stop taking and consult a physician. If you are taking any prescription medications, consult your physician prior to use.
Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.
Store in a cool, dry place.

Suggested Use: Adults: 1 softgel three times daily with meals for four weeks. Thereafter, 1 softgel twice daily for four to six months. If necessary increase to 1 softgel three times daily. Adolescents: 10 to 17 years of age 1 softgel twice daily for four months. Children: 6 to 9 years of age 1 softgel daily. Not for use by children under the age of 6. You may begin the regimen anew as desired.

SKU Count/Type Suggested Retail
PF0587 30 softgel $ 26.98
PF0588 60 softgel $ 47.50


Planetary Herbals does not sell directly to consumers.
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MigraComfort™
Supports Cerebral Comfort . . .


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